Purdue Vaccine Study – what you should know

Please print and give your veterinarian a copy of the letter below, regarding the research being done at Purdue University Veterinary School under the direction of Dr. Larry Glickman. This study started in the late 1990’s, the study of Vaccine-Induced Autoimmunity in the dog and there is already some evidence of thyroid, heart, bone disease (HOD like symptoms) due to vaccines. This information has been hidden in plain sight all of this time.

When anyone tells you ‘the science is settled, vaccines work’, that in my opinion is a gigantic reductionist view of a very complex topic, and false. No science is ever settled, that is why it is science, forever being studied, forever finding out new things. Look, we spent over 2,000 years believing the Earth was the center of the Universe, and flat, now look at what we currently know to be true. Ever evolving, ever changing, that is science.

Vaccine manufacturers are going to fight back because the more they sell the more money they make, that is a fact. Safe vaccine schedules and cleaner vaccines are not good financial choices for them, so therein lies another layer of complexity, or insidious behavior, however you choose to look at it.

Many breeders, trainers, and family pet owners have known this for years, they have told their veterinarians about reactions, and have been advocates for legitimate studies, safer schedules, and the end to over vaccination. Finally someone listened. Thank you.

This information is important, please share, pass along, and make sure to give your veterinarian a copy, All the best, Nancy



A Possible Etiology of Autoimmune Diseases

By William R. La Rosa, M.D. Trustee- Hayward Foundation – The Hayward Foundation is dedicated to research and eradication of human genetic diseases.

There is much anecdotal hearsay about the safety of vaccines in dogs as well as in humans.

The Vaccine Safety Committee recently emphasized the need for more definitive research on possible adverse effects during the development of new vaccines and vaccine combinations.

(National Academy Press, Washington D.C. 1994).

When a dog vaccine safety issue was brought to our attention by Laura Kiaulenas, a prominent Harlequin Great Dane breeder, and after reading articles by Jean Dodds DVM, we decided to fund a study to prove or disprove the supposition of multiple diseases, acute and chronic, caused by vaccination.

If indeed, many breeders are correct, then is the dog a canary sentinel, and are human similarly being affected, and if so can we identify the dog or human who is genetically susceptible to these reactions ?

We were fortunate that prominent and respected researchers, Drs. Larry T. Glickman, Harm HogenEsch, Juan I. Azona-Olivera, J. Catherine Scott-Montcrieff, and Paul W. Snyder of Purdue University, School of Veterinary Medicine, agreed to undertake the study.

The results are enlightening and they are enthusiastically working on the second phase, a study of longer duration.

They presented a paper to the International Veterinary Vaccines and Diagnostics Conference, July 27 – 31, 1997, in Madison, Wisconsin, hosted by the University of Wisconsin and at the International Canine Immunogenetics and Immunologcal Diseases Conference at the School of Veterinary Medicine at UC Davis, July 31-98 – August 2, 1998.

These proceedings have been published in “Advances in Veterinary Science and Comparative Medicine.” Another manuscript “Induced Serum Auto antibodies in Young Beagles”, has been submitted to a human immunology journal “Clinical Immunology and Immmunopathology.”

Their study was based on the increasing concern among veterinarians and breeders that current vaccination protocols adversely affect the health of dogs.

This concern has largely been based on an overwhelming anecdotal and circumstantial evidence.

They studied the effects of routinely used vaccination protocol on the immune and endocrine systems of Beagles. One control group was not vaccinated and the other group was vaccinated with a commercial multivalent vaccine at 8, 10, 12, 16, and 20 weeks of age and with a rabies vaccine at 16 weeks of age.

A definition of Autoimmune disease is now necessary.

In dogs as well as humans, the body sometimes forms antibodies against itself (self antigens) which can lead to diseases of the pancreas (diabetes), thyroid (Hashimoto’s Disease), collagen and fibronectin (Scleroderma, Lupus), cardiolipin (Cardiomyopathy), etc.


VACCINE SAFETY A Possible Etiology of Autoimmune Diseases (1994 – 2004)

Below is a copy of Dr. LaRosa’s statement regarding the study Purdue Study. He is a Trustee for the Hayward Genetics Foundation, they are funding in part this research.

By William R. La Rosa, M.D. (Trustee)

The body literally attacks itself to cause the autoimmune disease. The vaccinated group developed significant levels of autoantibodies against fibronectin, laminin, DNA, albumin, Cytochrome C, transferrin, cardiolipin, collagen. The re-sponses varied among individual animals, probably reflecting genetic differences.

The clinical significance of those autoantibodies remains to be determined,but speculation must be that something in the vaccines is one of the etiologies (in the genetically susceptible dog) of such diseases as Cardiomyopathy, Lupus Erythematosus, Glomerulonephritis, etc.

I apologize for using these technical terms but this is a complex study and adds validity to the report.

Autoimmune diseases are quite common in dogs as well as in humans, but much easier to study in dogs, especially since various breeds have genetic susceptibility or predisposition.

The high prevalence of autoimmune disease in specific breeds makes it easier to search for the genetic markers.

Humans are much more diverse and therefore more difficult to study.

We hope that many Breed Associations and the AKC Foundation will join us in expanding these studies with the needed research funds. Longer term studies are needed to determine the clinical importance of vaccine-induced autoantibodies and to identify markers of genetic susceptability.

These are truly remarkable results.

The next step is to study the development of safer vaccines, or possibly modify the recommended dosages, and the timing of vaccinations. Many vaccines, including a vaccine for use in humans, contain fibronectin. This appears to be a common contaminant.

Other antigens will be studied.

A general theme of the Conference was that vaccine immunity lasts longer than the manufacturer claims; rabies is probably effective for at least 3 years and we are probably over-vaccinating our dogs. Even the vaccine industry tells you that there is never 100% protection. Therefore disease is seen even in vaccinated groups.

In Europe, vaccines are prohibited once the disease is eliminated because the fear of reversion to virulence of the modified live virus.

Autoimmune diseases in dogs are clinically similar to those in humans. We hope that Veterinary and Medical Schools will continue and expand these preliminary research studies.

Our companion dogs are crashing all around us and maybe we are now finding one of the sources of the problems.

It has been so easy to point fingers at breeders but they may not be entirely at fault.

Let us continue this important research to help our future generations of dogs and possibly children.

Yes, indiscriminate breeding can genetically predispose the dog but is the trigger mechanism indiscriminate vaccinations ?

My personal interpretation of the above information in brief is:

1 )These studies appear to support the conclusions of some breeders that multiple vaccinations may be harmful to dogs. Be cautious and keep current in the scientific literature.

2 ) Current vaccines induce autoantibodies. Contaminants may be part of the problem.

3 ) We need to research and explain the mechanism. Does it alter the DNA causing genetic abnormality or is the susceptible gene already in place ? Can we find the genetic marker to avoid the adverse reaction of vaccination?

4 ) The dog is a good model for study because different breeds already have susceptibility to specific diseases and genetic markers will be easier to find than in other diverse animals (and humans).

5 ) What is the solution or cure, and especially how is this applicable to humans.

6 ) Most current vaccines are effective in preventing disease, but they may be administered more frequently than is actually required.

15 Comments Add yours

  1. sarahsmilesalot says:

    I have seen studies that show our use of rabies vaccines alone are so over prescribed that what we subject our dogs to rvery three years, only is helpful every TEN years. The puppy dose is the same as a grown dog dose . Big pharma is everywhere.

    1. Nancy Tanner says:

      If everyone understood this, demanded TITERS before vaccination to see if it is even necessary, and pressured their veterinarians to learn more, then we would see real change.

      It is educating pet owners from the get go, what is for health and what is for profit. Nancy

    2. Fern says:

      They give the same dose to a 1lb pup and 160b dog

  2. Jenny H says:

    We need to do more to control the manufacturers and distributers of these vaccines.
    When I queried my vet abut the necessity for re-vaccination yearly, she told me that IF she did no recommend this to her clients THEN she would not be covered by the manufacturer’s insurance. And the annual vaccine was exactly the same as the triennial vaccine — the difference was in how long the insurance cover that came with it was.

    1. Nancy Tanner says:

      and how criminal is that … and to add insult to injury, 16-33% of a veterinary annual income is vaccination. This needs to be flipped.

  3. Samaara says:

    Over the past five months I have been working with my dog Sampson after he became lame in his right rear leg. He was ultimately diagnosed with an autoimmune disorder. He was prescribed prednisone and other medications that almost killed him. For the past two months I’ve shifted him to a whole food diet, added liver support hydrosols and milk thistle tea. He has made a steady drug-free recovery. He is now starting acupuncture. The very first thing my new holistic vet said to me was no more vaccines for Sampson for the rest of his life. He is now 11. As pet owners we try to do the best for our pets. I’ve struggled this fall because what I was told to give Sampson to make him well was actually killing him. But I learned I am Sam’s advocate and Theodore’s and any future pets of mine. Thank you for getting he information out there.

    1. Nancy Tanner says:

      Hi Samaara, I am glad to hear that Sampson is making a recovery of sorts, may this continue. Sometimes it is the preventative stuff that acts like a trip wire for disease. If only we did less in the way of pharmaceuticals, and more in the way of real nutrition …. ❤

  4. Ernie Fender says:

    This article, after all the gobble gook does not answer the real question.
    Safe or not safe.
    More studies need to be done by real scientists and not innuendo from uneducated breeders.

    Is there a problem? Sure, but sighting papers from the 1990’s is really not very helpful.

    1. Nancy Tanner says:

      Hi Ernie, I don’t often try to write in gooble gook, but if I did, perhaps it is a new foreign language I should investigate.

      This is not a black and white issue, safe or unsafe. There are years worth, and mountains of data that was done by pharma for their own benefit and gain, and by people holding patents, again for their own patent and gain.

      This study is known by the AVMA, all veterinary students, and veterinarians, YET they keep promoting over vaccination. Why you ask? because 16-33% of a veterinarians income is based on vaccine visits.

      This study should be known by all breeders, and both dog and cat owners, so they can then make an informed choice.

  5. Michael Dym says:

    See my Facebook page for actual clinical case of combination Distemper vaccination trigger in 11 year old King Charles of heart failure demonstrating autoantibody production seen this week. Michael Dym, VMD

    1. Nancy Tanner says:

      HI Michael, could you share that link with me, I did not see it. Nancy

  6. Sheila Kleckner says:

    My 4 yr old cocker spaniel was just diagnosed 2 days ago with IMHA. He was healthy, happy and full of life one day and the next day he was dying. His vet can not find any other reason for this disease but his vaccinations. If anyone can give me information on your study and IMHA as part of the issues with vaccines I would be extremely appreciative. We are completely devastated. Thank you!

    1. Nancy Tanner says:

      Sheila, I will send you an e-mail, thank you, Nancy

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